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How VeRelief Works: A Deep Dive into Vagus Nerve Stimulation – Hoolest Inc.
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How VeRelief Works: A Deep Dive into Vagus Nerve Stimulation

🧠 Top Insight: VeRelief stimulates the auricular branch of the vagus nerve—sending calming signals straight to the brain to rapidly trigger GABA release and full-body downregulation.

If you’ve ever wondered how vagus nerve stimulation (VNS) actually works—or why VeRelief feels like an “off switch” for stress—this is the science behind the sensation.

Let’s break it down anatomically and functionally so you can understand exactly what’s happening when you turn this device on.


🧬 The Anatomy: Ascending vs. Descending Vagus Nerve

VeRelief specifically targets the auricular branch of the vagus nerve—located near the outer ear. This branch is 100% afferent (aka ascending), meaning it only sends signals up to the brain.

Contrast this with the cervical vagus nerve (on the front of your neck), which contains efferent (descending) fibers that send signals down to the heart, lungs, and gut.

Here’s the signal path when you use VeRelief:

  1. Stimulate the auricular vagus nerve.

  2. Signals travel to the nucleus tractus solitarius (NTS) and locus coeruleus (LC) in the brainstem.

  3. These brainstem hubs activate regions like the:

    • Amygdala (panic/fear)

    • Prefrontal cortex (overthinking/worry)

    • Hippocampus (mood/memory)

This is the upstream half of your parasympathetic nervous system’s command center. But what happens next?


⚙️ The Function: How Stimulation Triggers Calm

Step 1: Electrical Pulses Trigger Action Potentials

VeRelief uses low-frequency electrical pulses (not vibration, not heat) to stimulate the nerve. This matches the brain’s natural signaling language—electricity—and initiates what’s called an action potential.

The pulses fire consistently along the nerve, activating the full pathway from skin to brainstem.

⚠️ High-frequency stimulation does not produce this effect—in fact, it may suppress the nerve.

Step 2: GABA Receptors Open in the Brain

Once the brainstem receives the signal, it sends instructions to open GABA receptors in the emotional regulation centers of the brain.

GABA (gamma-aminobutyric acid) is your brain’s natural brake pedal. When GABA receptors open, they absorb free-floating GABA and immediately begin to shut down the fight-or-flight response.

Without open GABA receptors, your brain can’t relax—no matter how many supplements you take.

Step 3: The Body Responds via the Descending Vagus Nerve

Once GABA calms the mind, a new signal travels down the cervical vagus nerve to your heart, lungs, and gut. This triggers the release of acetylcholine, which:

  • Slows heart rate

  • Slows breathing

  • Enhances digestion

This entire sequence is what people refer to as "activating the parasympathetic response."


🧪 What If Your Nervous System Is Broken?

Sometimes, the system doesn’t work as expected. Here are common dysfunctions and how to support them:

Issue Symptom Solution
Weak Ascending Vagus Always in fight-or-flight, fatigued Use auricular VNS daily (like VeRelief)
GABA Deficiency Can’t calm down, panic attacks Use sublingual liposomal GABA + VNS
Weak Descending Vagus Body feels wired, even if mind is calm Deep breathing (long exhales) or cervical VNS
Acetylcholine Deficiency Poor digestion, high HR, stress after eating Supplement with acetylcholine or eat egg yolks

💡 Why VeRelief Works (and Who It’s For)

VeRelief is designed for:

  • People stuck in mental overdrive (panic, looping thoughts)

  • People needing fast relief (calm in 15–30 seconds)

  • People who want to train their nervous system over time

It’s not for everyone. If you’re dealing with severe descending vagus dysfunction or neurotransmitter deficiencies, you may need to stack VeRelief with:

  • Liposomal sublingual GABA

  • Deep breathing (4- to 6-second inhales, 8- to 12-second exhales)

  • Acetylcholine support

💡 Pro Tip: Try VeRelief while doing slow exhales and using GABA—it stimulates both the ascending and descending vagus branches for a full-system reset.


🧠 Final Thoughts: This Isn’t Just Calm—It’s Neuroengineering

VeRelief works because it speaks your nervous system’s native language: electricity. It activates your GABA system, triggers real downregulation, and helps your body recover faster from daily stress.

For those chasing high performance or simply looking for peace of mind—this isn’t a gimmick. It’s a portable, science-backed way to calm your body and brain, anytime.


Want to try it?

Explore Hoolest products—and feel the difference.

Have more questions? Drop them in the comments or reach out—we’re here to support your nervous system recovery.

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